Innovating Treatments. Transforming Lives.
Welcome to the Infectious Disease and Drug Discovery (IDDD) Lab at Texas Southern University—where groundbreaking science meets real-world impact. Our mission is to develop novel therapeutic solutions for global infectious diseases while advancing innovation in biomedical research.
Welcome to IDDD
Welcome to the Infectious Disease and Drug Discovery (IDDD) Lab at Texas Southern University, where groundbreaking science meets real-world impact. Our mission is to develop novel therapeutic solutions for global infectious diseases while advancing innovation in biomedical research.
Undergraduate research fellowships open for 2025
The IDDD Lab at Texas Southern University is a leading research initiative focused on the discovery and development of new treatments for infectious diseases. As part of TSU’s College of Pharmacy and Health Sciences, we combine translational science, and training of the next generation of biomedical researchers.
Mission
To develop next-generation therapeutics targeting infectious diseases that disproportionately impact underserved communities.
Vision
To be a national hub for discovery and innovation in infectious disease research.
Meet the Principal Investigator
"At IDDD, we believe drug discovery should reflect the communities it serves. We are proud to lead cutting-edge research and inclusive training that advances science and social impact."
Dr. Omonike Olaleye, PI
Infectious Diseases and Drug Discovery (IDDD) Lab,
Senior Associate Vice President for Research and Innovation,
Texas Southern University
Research Focus Areas
Tuberculosis (TB)
Developing inhibitors for drug-resistant Mycobacterium tuberculosis.
HIV/AIDS
Novel integrase and protease inhibitors using molecular modeling
COVID-19 & Coronaviruses
Small molecule antivirals and spike protein neutralizers
Antimicrobial Resistance (AMR)
Investigating β-lactamase inhibitors and resistance mechanisms.
Quick Facts
Pubications
10+ peer-reviewed papers since 2020
Research
$7.8M in active research funding
Drug Discovery Platforms
Target Identification & Validation
Genomic and proteomic screening
High-Throughput Screening
50,000-compound library screening facility.
Computational Drug Design
AI-driven lead optimization and molecular docking.
Natural Products Chemistry
Isolating antimicrobial agents from local flora.
Our Facilities
Biocontainment Lab
BSL-2 with selective access for mycobacteria and viral assays
HTS Screening Core
Robotics-supported compound screening platform
Spectroscopy Suite
NMR
Computational Drug Discovery Lab
Molecular docking, pharmacophore modeling, and ADMET prediction, HPC
Partnerships & Collaborations
Institutional Collaborations
Organizational Collaborations
Collaborations with biotech startups on antiviral screening and formulation studies.
Community Partners
- Local clinics providing isolates for AMR research
- Public health outreach in underserved Houston neighborhoods
Join Our Lab
You're invited to join the Infectious Disease Drug Discovery and Development (IDDD) Lab at Texas Southern University! Our lab is a dynamic research initiative dedicated to discovering and developing innovative treatments for infectious diseases. If you're passionate about making a difference in global health, we encourage you to explore our lab and consider joining our team. Together, let's advance scientific discovery and improve human health!